Chronic Pain Market Epidemiology Report 2025-2035: Drugs Pipeline, Therapies, and Forecast

The report provides a detailed analysis of the current chronic pain marketed drugs and late-stage pipeline drugs.

BROOKLYN, NY, UNITED STATES, July 16, 2025 /EINPresswire.com/ -- The chronic pain market size reached a value of USD 21.8 billion in 2024. Looking forward, IMARC Group expects the 7MM to reach USD 29.9 billion by 2035, exhibiting a growth rate (CAGR) of 2.90% during ​2025-2035​.

The chronic pain market is set for robust development in 2025 fueled by new technologies and focus on an aging population. These demographics have a greater emphasis on personalized healthcare and chronic illness management. Rates of chronic pain conditions straddling cross many geographies to over millions, with rising awareness, healthcare systems are evolving to provide high value and accessible holistic care. This is creating a market shaped by balanced innovation, patient-centric goals, and clinical rigor. Investments on non-opioid therapies remain one of the most prominent trends in the chronic pain sector. With the risk of dependency on opioids being a hot button issue, pharmaceutical and biotech companies are seeking pain relief alternatives that do not come with an addiction risk. These include new small molecules, biologics, and neuromodulation therapies. For example, the anti-nerve growth factor biologics are working their magic on osteoarthritis pain, and specialized ion channel blockers are working on neuropathic pain. The focus of these new medications is to achieve long lasting pain relief while minimizing side effects and providing safer long term options.

Another area of importance is the expansion of telemedicine and digital health aids in pain management. Remote care, symptom monitoring, and adherence support are possible through virtual platforms. Patient’s activity and treatment response are also monitored through wearable sensors and mobile applications. Data gathered through these systems is helping in the development of tailored treatment. Physicians are now able to make real time adjustments to treatment and better communication with patients and providers is being fostered. This kind of transformation, especially for poorly served areas, removes hurdles to accessing care.

The development of new therapies for chronic pain is rapidly progressing, including stimulant devices, radio frequency treatment and other chronic pain stimulants. The spinal cord and peripheral nerve stimulators will be more sophisticated and easier to operate by 2025. These devices have shown to be more effective and comfortable to patients due to innovations on remote programming, design, and battery life. They are very helpful for back pain, complex regional pain syndrome, and even some forms of cancer pain. Moreover, the chronic pain market is seeing new methods that add to existing therapies. Pain management is being extended by including more forms of rehabilitation, acupuncture, cognitive behavioral therapy, and mindfulness into pain clinics. This way, both the mind and the body work together to control pain. Patients suffer less from psychological distress and spend less money on medication due to the improved long-term quality of life.

In terms of geography, the United States and Europe continue to dominate the adoption of new methods for pain management along with the regulatory support and infrastructure. APAC is swiftly catching up, however, with increased spending on healthcare, a growing middle class, and more focus on chronic diseases such as diabetes. China, Japan, and India are expanding their reimbursement programs and creating greater opportunities for new and traditional pain management techniques. Although there are positive advancements, the chronic pain market encounters challenges. Specialized biologics and medical devices are still costly. Innovative treatments are not well covered by insurance policies in many areas, which restricts patient access. Newer therapies also require clinical evidence demonstrating long-term benefits and cost-effectiveness, which is needed for approval and market adoption.
The ongoing complexities of chronic pain create additional obstacles. Because the ways people experience and cause pain are so diverse, it is hard to create universal solutions. This pushes the shift towards medication precision pain tailoring to genetics, the type of pain, lifestyle, and even patients’ preferences. The advances of pain undergo further classification and biomarkers are aiding physicians in determining the most effective treatment methods for each of their patients.

The 2025 projection shows the chronic pain market shifting from treating symptoms to more proactive and tailored approaches for individual patients. Ponytail non-opioid drugs, new advanced devices, digital health innovations, and integrative care models are transforming how pain is treated. This results in enhanced patient safety and improved quality of life and increased autonomy over healthcare. From the standpoint of healthcare providers and payers, it offers smart resource allocation and better long-term outcomes. Sustained growth, transformative market changes, and research innovation are all poised for the coming years.

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This report also provides a detailed analysis of the current chronic pain marketed drugs and late-stage pipeline drugs.

In-Market Drugs

Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance

Late-Stage Pipeline Drugs

Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance

Kindly note that the drugs in the above table only represent a partial list of marketed/pipeline drugs, and the complete list has been provided in the report.

Competitive Landscape with key players:

The competitive landscape of the chronic pain market has been studied in the report with the detailed profiles of the key players operating in the market.

Pfizer
Biodelivery Sciences
Astrazeneca
Purdue Pharma
Braeburn Pharmaceuticals
Tris Pharma
Eli Lilly and Company
Vertanical GmbH

7 Major Countries Covered

United States
Germany
France
United Kingdom
Italy
Spain
Japan

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Elena Anderson
IMARC Services Private Limited
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